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OVERVIEW

Advances in antiretroviral therapy (ART) have transformed human immunodeficiency virus (HIV) into a chronic disease, with life expectancies in patients with HIV/Acquired Immune Deficiency Syndrome (AIDS), who receive optimal therapy, nearing that of the uninfected population. These advances have also resulted in the development of highly efficacious prophylactic agents (eg, preexposure prophylaxis [PrEP]) that are able to reduce the risk of HIV acquisition in high-risk populations by more than 90%. However, there are pharmacological challenges in managing ART and implementing novel PrEP in an aging HIV population as this population oftentimes has multiple comorbidities that require concomitant medications. As drug therapy experts and clinicians with frequent patient contact, pharmacists are ideally suited to fulfill the growing needs related to HIV prevention and life-long treatment management for this patient population. Through interactive case-based presentations and expert discussion, this archived webcast activity will review the advances in the management of patients with HIV/AIDS. Specifically, this activity will address efficacy, safety, and patient eligibility for PrEP, as well as strategies to manage adherence issues, adverse events, and drug-drug interactions.

GOAL

The goal of this activity is to provide pharmacists with the most up-to-date treatment strategies to optimize management and improve outcomes for patients with or at risk for acquiring HIV.

TARGET AUDIENCE

This activity is designed community pharmacists, specialty pharmacists, infectious disease pharmacists, health systems pharmacists, managed care pharmacists and other pharmacists involved in the treatment of patients with HIV. No prerequisites required.

LEARNING OBJECTIVES

The University of Tennessee College of Pharmacy takes responsibility for the content, quality, and scientific integrity of this CPE activity. At the conclusion of this activity, the participant should be able to:

• DESCRIBE PrEP as a method to prevent HIV acquisition, including efficacy, safety, and candidate eligibility.
• ASSESS strategies to manage ART, including initiation, agent selection and modifications, in patients with comorbid medical and/or substance abuse conditions.
• EVALUATE methods to identify and manage DDIs, AEs, and medication errors within ART regimens.
• IMPLEMENT pharmacist-driven strategies to assist patients overcome structural, social and medical barriers to increase screening, prevention, and adherence to HIV therapy.

CREDIT DESIGNATION STATEMENT

The University of Tennessee College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. Successful completion of this application-based activity will provide a statement for 1.5 contact hours of credit (0.15 CEUs) and will be available at the completion of the activity. Successfully completing the activity and receiving credit includes: 1) reading the learning objectives and faculty disclosures; 2) studying the educational activity; 3) evaluating the activity; and, 4) completing the self-assessment instrument with a score of at least 70%. UAN:  0064-0000-17-218-H02-P. CE credit will be submitted to the NABP CPE Monitor within 30 days.  It is recommended that you check your NABP CPE Monitor e-profile database 30 days after the completion of any CE activity to ensure that your credits are posted.

NABP e-PROFILE ID NUMBER: Pharmacists or pharmacy technicians with questions regarding their NABP e-Profile or CPE Monitor should refer to the FAQ section on the NABP website: https://nabp.pharmacy/cpe-monitor-service/cpe-monitor-faqs/. To receive credit for your participation in this activity, all pharmacists must include their NABP e-Profile ID number, along with their month and date of birth. If incorrect information is provided, this will result in "rejected" status from the CPE Monitor. It is the responsibility of the participant to notify The University of Tennessee (within the 60 day submission timeframe) of their corrected information. Otherwise, the completed CE will not be accepted by the CPE Monitor.

Please allow up to 30 days for your credit to appear on CPE Monitor.

Type of Activity: Application

Published: November 21, 2017
Expires: November 21, 2018
Media: Internet

Fee Information: There is no fee for this educational activity.

Estimated time to complete activity: 90 minutes

HOW TO EARN CREDIT

Participants must complete the activity as described above in the Credit Designation Statement. To answer the questions, click on your selected choice for each answer then proceed to the next question. We recommend that you print a copy of your answers before you submit them to us. Once completed, click on Submit Post-test at the bottom of the page. Your post-test will automatically be graded. If you successfully complete the post-test (score of 70% or higher), your statement of CE credit will be made available immediately. Click on View Certificate and print the CE statement for your records. If you receive a score lower than 70%, you will receive a message notifying you that you did not pass the post-test. You will have 2 opportunities to pass the post-test.

FULL DISCLOSURE POLICY AFFECTING CPE ACTIVITIES

As an accredited provider by the Accreditation Council for Pharmacy Education (ACPE), it is the policy of The University of Tennessee College of Pharmacy to require the disclosure of the existence of any significant financial interest or any other relationship a faculty member or a sponsor has with the manufacturer(s) of any commercial product(s) discussed in an educational presentation. The Course Director and Participating Faculty reported the following:

PARTICIPATING FACULTY

Theodore J. Cory, PhD, PharmD
Assistant Professor
Department of Clinical Pharmacy
University of Tennessee Health Sciences Center
Memphis, Tennessee
Dr Cory reports having no significant financial or advisory relationships with corporate organizations related to this activity.

Anthony Podany, PharmD
Assistant Professor
Antiviral Pharmacology Laboratory
University of Nebraska Medical Center College of Pharmacy
Omaha, Nebraska
Dr Podany reports having no significant financial or advisory relationships with corporate organizations related to this activity.

OFF-LABEL PRODUCT DISCUSSION

In accordance with ACPE Criteria for Quality, the audience is advised that authors in this CPE activity may include reference(s) to unlabeled, unapproved, or investigational uses of therapeutic agents or biomedical devices. The presenters will inform the participant of when they discuss or reference an unapproved, unlabeled, or investigational use of therapeutic agent or biomedical device.

DISCLAIMER STATEMENT

The opinions and recommendations expressed by faculty and other experts whose input is included in this activity are their own. This activity is produced for educational purposes only. Use of The University of Tennessee College of Pharmacy name implies review of educational format, design, and approach. Please review the complete prescribing information of specific drugs or combinations of drugs, including indications, contraindications, warnings, and adverse effects, before administering pharmacologic therapy to patients.

GRIEVANCE POLICY

A participant, sponsor, faculty member, or other individual wanting to file a grievance with respect to any aspect of an activity sponsored or cosponsored by The University of Tennessee College of Pharmacy may contact the Associate Dean for Continuing Education in writing at gfarr@utasip.com. The grievance will be reviewed and a response will be returned within 45 days of receiving the written statement. If not satisfied, an appeal to the Dean of the College of Pharmacy can be made for a second level review.

ACTIVITY

The following is an interactive case simulation designed to help you gauge your basic knowledge of the topic and then direct you to areas you may need to focus on. It consists of 3 sections: an unaccredited pre-test, an interactive case study, and a CPE post-test, and evaluation. All 3 sections must be completed to receive CPE credit. A statement of credit will be available online immediately following successful completion of the activity.

REQUIRED COMPUTER HARDWARE/SOFTWARE

Please ensure the computer you plan to use meets the following minimum requirements:

• Operating System: Windows 98 or higher & Macintosh 2.2 or higher
• Internet Browser (Mac &/Windows): Internet Explorer 6.0 or higher, Google Chrome, Safari 5.0.6 or higher, Firefox 3.0.3 or higher & Opera 5 or higher
• Broadband Internet connection: Cable, High-speed DSL & any other medium that is internet accessible
• Peripherals: Computer speakers or headphones
• Monitor Screen Resolution: 320 x 480 or higher
• Media Viewing Requirements: Adobe Reader, Microsoft Powerpoint, Flash Player & HTML5

TABLE OF CONTENTS

Preassessment

HIV/AIDS Goals:
The Critical Role of the Pharmacist in the Continuum of Care
Theodore J. Cory, PhD, PharmD

Attaining HIV Goals:
Improving Pharmacological Management and Treatment Success
Theodore J. Cory, PhD, PharmD

Attaining HIV Goals:
Preventing HIV Acquisition
Anthony Podany, PharmD

Pharmacist-Derived Strategies to Overcome Barriers to Care
Anthony Podany, PharmD

Question & Answer Session
Theodore J. Cory, PhD, PharmD, and Anthony Podany, PharmD

Conclusions

Postassessment and Evaluation

What you are about to see is a previously recorded live webcast. Please note that only "home study" credit will be awarded for participating in this archived presentation. No "live" credits are available.