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Nonwarfarin Oral Anticoagulants (NOACs): The Clinical Pharmacist's Perspective

Release Date: March 18, 2016
Last Reviewed: February 23, 2016
Expiration Date: March 18, 2017

Time to Complete Activity: 1.0 hour

This activity is jointly provided by Global Education Group and Paradigm Medical Communications, LLC.
UMA            Paradigm


Paul P. Dobesh, PharmD
Professor of Pharmacy Practice
University of Nebraska Medical Center College of Pharmacy
Omaha, NE

John Fanikos, RPh, MBA
Director of Pharmacy, Business
Brigham and Women's Hospital
Boston, MA

Sarah A. Spinler, PharmD, FCCP, FCPP, FAHA, FASHP, AACC, BCPS-AQ Cardiology
Professor of Clinical Pharmacy
Philadelphia College of Pharmacy
University of the Sciences
Philadelphia, PA


This activity has been designed to address the educational needs of clinical, health-system, and other pharmacists interested in the management of patients with or at risk of developing thrombosis.

Learning Objectives

Upon proper completion of this activity, participants should be better able to:

  • Outline evidence-based strategies for assessing thrombosis and bleeding risk to identify appropriate candidates for oral anticoagulation.
  • Apply current clinical evidence to select the most appropriate oral anticoagulant for individual patients considering comorbidities and patient preferences.
  • Describe evidence-based strategies for ensuring the safe use of nonwarfarin oral anticoagulants.
  • Identify ways pharmacists can be actively involved in ensuring adherence to oral anticoagulation therapy.

Table of Contents

Call to Action: Opportunities to Improve Oral Anticoagulant (OAC) Therapy
Individualized Use of NOACs for SPAF
Individualized Use of NOACs for VTE
Special Considerations and Challenges With NOAC Use
Ensuring Adherence to Therapy: The Importance of Patient Education and Monitoring Across Care Transitions

Accreditation Statement

acpeGlobal Education Group is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

Credit Designation Statement

Global Education Group designates this continuing education activity for 1.0 contact hour (0.10 CEUs) of the Accreditation Council for Pharmacy Education.
(Universal Activity Number – 0530-9999-15-183-H01-P)

This is a knowledge-based activity.

For information about the accreditation of this program, please contact Global at (303) 395-1782 or inquire@globaleducationgroup.com.

Disclosure of Commercial Support

This activity is supported by independent educational grants from Boehringer Ingelheim Pharmaceuticals, Inc. and Daiichi Sankyo, Inc.

Instructions for Participation

To receive CPE credit, you must:

  • Follow instructions to register or log in with your professional information and complete the pretest. Please make sure you provide your date of birth and NABP number.
  • View the online activity in its entirety.
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have 2 opportunities to successfully complete the posttest.
  • All credit information will be uploaded into CPE Monitor within 30 days.

For questions regarding CPE credit, contact the Paradigm CME Department at (845) 398-5949.

There is no fee required for participation in this activity.

Hardware/Software Requirements

Please ensure the computer system you plan to use meets the following minimum requirements:

  • Operating system: Windows 98 or higher & Macintosh 2.2 or higher
  • Internet browser (Mac & Windows): Internet Explorer 6.0 or higher, Google Chrome, Safari 5.0.6 or higher, Firefox 3.0.3 or higher, & Opera 5 or higher
  • Broadband internet connection: Cable, High-speed DSL & any other medium that is internet accessible
  • Monitor screen resolution: 320 x 480 or higher
  • Media viewing requirements: Adobe Reader, Microsoft PowerPoint, Flash Player & HTML5

Disclosure and Resolution of Conflict of Interest

Global Education Group (Global) and Paradigm Medical Communications, LLC (Paradigm) require instructors, planners, managers, and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity.  All identified conflicts of interest are thoroughly vetted by Global and Paradigm for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations. 

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CPE activity:

Name of Faculty or Presenter Reported Financial Relationship
Paul P. Dobesh, PharmD Grant/Research Support: Daiichi Sankyo, Inc and Eli Lilly Company Alliance
Retained Consultant: Boehringer Ingelheim Pharmaceuticals, Inc,
Bristol-Myers Squibb Company/Pfizer Inc, Daiichi Sankyo Inc, Janssen Pharmaceuticals, Inc
John Fanikos, RPh, MBA Retained Consultant: BD Rx, Inc, Boehringer Ingelheim Pharmaceuticals, Inc,
Portola Pharmaceuticals, Inc
Sarah A. Spinler, PharmD, FCCP, FCPP, FAHA, FASHP, AACC, BCPS-AQ Cardiology Retained Consultant: Boehringer Ingelheim Pharmaceuticals, Inc, Daiichi Sankyo Inc, Portola Pharmaceuticals, Inc

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CPE activity:

Name of Planner or Manager Reported Financial Relationship
Amanda Glazer, PhD No financial relationships to disclose
Laura Gilsdorf No financial relationships to disclose

Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global and Paradigm do not recommend the use of any agent outside of the labeled indications. 

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

Terms of Use and Privacy Policy


The materials provided for this activity are for informational purposes only, and should not be used for diagnosis or treatment of a health problem without consulting a licensed medical professional. Any views or opinions presented are solely those of the faculty, and do not necessarily represent those of Global Education Group or Paradigm Medical Communications, LLC. References to any entity, product, service, or source of information on this website should not be considered an endorsement, either direct or implied, by Global or Paradigm. Global and Paradigm accept no liability for the content referenced in this activity.

Privacy policy

Global and Paradigm are committed to protecting the privacy of those who participate in the activities (herein referred to as "website") located at www.paradigmmc.com. The information below describes the security of the website for safeguarding personal information and the rationale for collection and use of personal information.

Security/safeguarding personal information

This website has physical and procedural safeguards in place to prevent unauthorized access to personal information used to access this website.

Collection and use of your personal information

The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing the program. Required items include first name, last name, degree, and email address. These items are necessary. Participants are also required to complete an evaluation of the CME activity. All evaluative information submitted is collected and retained, and used by Global and Paradigm to continuously improve the learning experience.

Global Education Group and Paradigm Medical Communications, LLC do not transfer, sell, or share personal information with outside parties. Global Education Group and Paradigm will not otherwise disclose personal information unless required to in a legal process. Global and Paradigm staff members review individual test results to the extent necessary to record and track participants' credits.

Contact Us

If you have any questions or comments, please email us at contactus@paradigmmc.com.

© 2016 Paradigm Medical Communications, LLC, except where noted. Content may not be reproduced in whole or part without the express written permission of Paradigm Medical Communications, LLC.