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Optimizing the Management of Hyperkalemia:
An Update for Health-System Pharmacists

Provided by The University of Tennessee College of Pharmacy, in cooperation with ASiM.
Supported by an educational grant from ZS Pharma.


Though hyperkalemia occurs in up to 10% of hospitalized patients, it often goes undetected in its subacute form. In its most severe presentation, hyperkalemia can cause respiratory paralysis and cardiac arrhythmias, both potentially fatal manifestations. Conventional treatments are limited by these potential fatal adverse events and the relative absence of clinical data regarding efficacy. Furthermore, treating hyperkalemia often involves the delay or discontinuation of the medications precipitating the electrolyte imbalance, medications that may be clinically necessary to treat an unrelated condition. Fortunately, 2 novel agents have emerged that may address some limitations of previous treatment options. Through interactive case-based presentations and expert discussion, this archived symposium will review recent advances and novel agents, as well as pharmacist-driven strategies to recognize patients who are at risk for hyperkalemia as well as strategies to optimize patients’ overall outcomes.


The goal of this activity is to provide health-system pharmacists with up-to-date comprehensive information on the recognition of patients at risk for and management of patients with hyperkalemia.


This activity is designed for health-systems pharmacists. No prerequisites required.


The University of Tennessee College of Pharmacy takes responsibility for the content, quality, and scientific integrity of this CPE activity. At the conclusion of this activity, the participant should be able to:

  • RECOGNIZE precipitating factors, including clinical conditions and medication therapy that contribute to the development of hyperkalemia.
  • IDENTIFY and compare available treatment options for acute and chronic hyperkalemia, including novel agents.
  • APPLY pharmacist-driven strategies to optimize treatment for hyperkalemia.


acpeThe University of Tennessee College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. Successful completion of this application -based program will provide a statement for 1.5 contact hours of credit (0.15 CEUs) and will be available at the completion of the activity. Successfully completing the activity and receiving credit includes: 1) attending the session; 2) watching, listening to, and participating in the educational activity; 3) completing the self-assessment instrument  with a score of at least 70%. UAN:  0064-0000-16-227-H01-P. CE credit will be submitted to the NABP CPE Monitor within 30 days.  It is recommended that you check your NABP CPE Monitor e-profile database 30 days after the completion of any CE activity to ensure that your credits are posted.

NABP e-PROFILE ID NUMBER: Pharmacists or pharmacy technicians with questions regarding their NABP e-Profile or CPE Monitor should refer to the FAQ section on the NABP website: https://nabp.pharmacy/cpe-monitor-service/cpe-monitor-faqs/. To receive credit for your participation in this activity, all pharmacists must include their NABP e-Profile ID number, along with their month and date of birth. If incorrect information is provided, this will result in "rejected" status from the CPE Monitor. It is the responsibility of the participant to notify The University of Tennessee (within the 60 day submission timeframe) of their corrected information. Otherwise, the completed CE will not be accepted by the CPE Monitor.

Please allow up to 30 days for your credit to appear on CPE Monitor.

Type of Activity: Application

Published: March 16, 2017
Expires: March 16, 2018

Media: Internet

Fee Information: There is no fee for this educational activity.

Estimated time to complete activity: 90 minutes


Participants must complete the activity as described above in the Credit Designation Statement. To answer the questions, click on your selected choice for each answer then proceed to the next question. We recommend that you print a copy of your answers before you submit them to us. Once completed, click on Submit Post-test at the bottom of the page. Your post-test will automatically be graded. If you successfully complete the post-test (score of 70% or higher), your statement of CE credit will be made available immediately. Click on View Certificate and print the CE statement for your records. If you receive a score lower than 70%, you will receive a message notifying you that you did not pass the post-test. You will have 2 opportunities to pass the post-test.


As an accredited provider by the Accreditation Council for Pharmacy Education (ACPE), it is the policy of The University of Tennessee College of Pharmacy to require the disclosure of the existence of any significant financial interest or any other relationship a faculty member or a sponsor has with the manufacturer(s) of any commercial product(s) discussed in an educational presentation. The Course Director and Participating Faculty reported the following:


Kristy N. Greene, PharmD, BCPS, BCCCP
Clinical Pharmacist Specialist, Neuroscience Critical Care Medicine
Emory University Hospital Midtown
Atlanta, Georgia
Dr Greene reports having no significant financial or advisory relationships with corporate organizations related to this activity.

Kelly Harbourt, PharmD, BCPS, BCCCP
Assistant Professor, Department of Clinical and Administrative Sciences
Notre Dame of Maryland University, School of Pharmacy
Clinical Pharmacy Specialist, Multitrauma ICU
University of Maryland Medical Center
Baltimore, Maryland
Dr Harbourt reports serving on the speakers' bureau for Eli Lilly and Company and Endo Pharmaceuticals Inc as an educator of chronic pain.


In accordance with ACPE Criteria for Quality, the audience is advised that discussions in this CPE activity may include reference(s) to unlabeled, unapproved, or investigational uses of therapeutic agents or biomedical devices, including, but not limited to, the following:

  • Albuterol
  • Calcium chloride
  • Calcium gluconate
  • Insulin
  • Loop diuretics
  • Sodium bicarbonate
  • Sodium zirconium cyclosilicate


The opinions and recommendations expressed by faculty and other experts whose input is included in this activity are their own. This activity is produced for educational purposes only. Use of The University of Tennessee College of Pharmacy name implies review of educational format, design, and approach. Please review the complete prescribing information of specific drugs or combinations of drugs, including indications, contraindications, warnings, and adverse effects, before administering pharmacologic therapy to patients.


A participant, sponsor, faculty member, or other individual wanting to file a grievance with respect to any aspect of an activity sponsored or cosponsored by The University of Tennessee College of Pharmacy may contact the Associate Dean for Continuing Education in writing at gfarr@utasip.com. The grievance will be reviewed and a response will be returned within 45 days of receiving the written statement. If not satisfied, an appeal to the Dean of the College of Pharmacy can be made for a second level review.


The following is an archived symposium, comprised of synced slides and audio, designed to help you gauge your basic knowledge of the topic and then direct you to areas you may need to focus on. It consists of 3 sections: an unaccredited pre-test, the symposium archive, and a CPE post-test, and evaluation. All 3 sections must be completed to receive CPE credit. A statement of credit will be available online immediately following successful completion of the activity.


Please ensure the computer you plan to use meets the following minimum requirements:

  • Operating System: Windows 98 or higher & Macintosh 2.2 or higher
  • Internet Browser (Mac &/Windows): Internet Explorer 6.0 or higher, Google Chrome, Safari 5.0.6 or higher, Firefox 3.0.3 or higher & Opera 5 or higher
  • Broadband Internet connection: Cable, High-speed DSL & any other medium that is internet accessible.
  • Peripherals: Computer speakers or headphones
  • Monitor Screen Resolution: 320 x 480 or higher
  • Media Viewing Requirements: Adobe Reader, Microsoft Power Point, Flash Player & HTML5

What you are about to see is a previously recorded live meeting.
Please note that only "home study" credit will be awarded for participating in this archived presentation.

No "live" credits are available.