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Managing Hyperkalemia in the Inpatient Setting:
Evolving Strategies to Ensure Optimal Patient Outcomes

Provided by The University of Tennessee College of Pharmacy, in cooperation with ASiM.
Supported by an educational grant from ZS Pharma, Inc.


Hyperkalemia occurs in up to 10% of hospitalized patients and is associated increased morbidity if left unaddressed. As a result, it is crucial to recognize and treat this electrolyte imbalance to optimize patient outcomes. Limited treatment options have rendered inpatient hyperkalemia management suboptimal, however, recently, several approved and investigational treatment options offer new options to patients with this electrolyte imbalance, changing the landscape of hyperkalemia treatment. Health systems pharmacists play a crucial role in both recognizing hyperkalemia and offending agents and in the treatment of patients diagnosed with hyperkalemia. This enduring roundtable activity will highlight recent advances in hyperkalemia pharmacotherapy and evaluate comprehensive strategies to recognize and manage hyperkalemia in clinical practice.


The goal of this activity is to provide up-to-date comprehensive information on novel pharmacotherapies and overall management of hospitalized patients with hyperkalemia for health system and other pharmacists.


This initiative has been designed to meet the educational needs of health system pharmacists, pharmacists, and other hospital based providers who are involved in the care of patients who present with or are at-risk for hyperkalemia. No prerequisites required.


The University of Tennessee College of Pharmacy takes responsibility for the content, quality, and scientific integrity of this CPE activity. At the conclusion of this activity, the participant should be able to:

  • RECOGNIZE precipitating factors, including clinical conditions and medication therapy that contribute to the development of hyperkalemia.
  • IDENTIFY novel hyperkalemia agents and how they compare with conventional treatment options.
  • FORMULATE treatment plans for correcting hyperkalemia according to etiology and physiology.


acpeThe University of Tennessee College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. Successful completion of this application-based program will provide a statement for 1.0 contact hour of credit (0.10 CEU) and will be available at the completion of the activity. Successfully completing the activity and receiving credit includes: 1) reading the learning objectives and faculty disclosures; 2) studying the educational activity; 3) evaluating the activity; and, 4) completing the self-assessment instrument with a score of at least 70%. UAN:  0064-0000-17-212-H01-P. CE credit will be submitted to the NABP CPE Monitor within 30 days.  It is recommended that you check your NABP CPE Monitor e-profile database 30 days after the completion of any CE activity to ensure that your credits are posted.

NABP e-PROFILE ID NUMBER: Pharmacists or pharmacy technicians with questions regarding their NABP e-Profile or CPE Monitor should refer to the FAQ section on the NABP website: https://nabp.pharmacy/cpe-monitor-service/cpe-monitor-faqs/. To receive credit for your participation in this activity, all pharmacists must include their NABP e-Profile ID number, along with their month and date of birth. If incorrect information is provided, this will result in "rejected" status from the CPE Monitor. It is the responsibility of the participant to notify The University of Tennessee (within the 60 day submission timeframe) of their corrected information. Otherwise, the completed CE will not be accepted by the CPE Monitor.

Please allow up to 30 days for your credit to appear on CPE Monitor.

The estimated time to complete this activity: 1.0 hour.

Release date: October 17, 2017

Expiration date: October 17, 2018


Participants must complete the activity as described above in the Credit Designation Statement. To answer the questions, click on your selected choice for each answer then proceed to the next question. We recommend that you print a copy of your answers before you submit them to us. Once completed, click on Submit Post-test at the bottom of the page. Your post-test will automatically be graded. If you successfully complete the post-test (score of 70% or higher), your statement of CE credit will be made available immediately. Click on View Certificate and print the CE statement for your records. If you receive a score lower than 70%, you will receive a message notifying you that you did not pass the post-test. You will have 2 opportunities to pass the post-test.


As an accredited provider by the Accreditation Council for Pharmacy Education (ACPE), it is the policy of The University of Tennessee College of Pharmacy to require the disclosure of the existence of any significant financial interest or any other relationship a faculty member or a sponsor has with the manufacturer(s) of any commercial product(s) discussed in an educational presentation. The Course Director and Participating Faculty reported the following:


Bentley C. Tate, MD (Moderator)
Director of Emergency Department
Colorado Plains Medical Center
Fort Morgan, Colorado
Dr Tate reports having no significant financial or advisory relationships with corporate organizations related to this activity.

Cynthia Bither, ACNP, ANP, MSN, AACC, CHFN
Chief Nurse Practitioner
Advanced Heart Failure Program
MedStar Washington Hospital Center
Washington, DC
Ms Bither reports serving on a speakers' bureau and on the advisory board, for one-time meetings, for Medtronic and Novartis AG.

Darla Klug Eastman, PharmD, BCPS
Associate Professor of Clinical Sciences
Drake University College of Pharmacy and Health Sciences
Clinical Pharmacist, Trauma and General Surgery
Iowa Methodist Medical Center
Des Moines, Iowa
Dr Eastman reports having no significant financial or advisory relationships with corporate organizations related to this activity.

Mazen Hanna, MD
Director, Heart Failure Intensive Care Unit
Co-Director, Amyloid Program
Cleveland Clinic
Department of Cardiovascular Disease
Cleveland, Ohio
Dr Hanna reports having no significant financial or advisory relationships with corporate organizations related to this activity.


In accordance with ACPE Criteria for Quality, the audience is advised that authors in this CPE activity may include reference(s) to unlabeled, unapproved, or investigational uses of therapeutic agents or biomedical devices. The authors will inform the reader of when they discuss or reference an unapproved, unlabeled, or investigational use of therapeutic agent or biomedical device.


The opinions and recommendations expressed by faculty and other experts whose input is included in this activity are their own. This activity is produced for educational purposes only. Use of The University of Tennessee College of Pharmacy name implies review of educational format, design, and approach. Please review the complete prescribing information of specific drugs or combinations of drugs, including indications, contraindications, warnings, and adverse effects, before administering pharmacologic therapy to patients.


A participant, sponsor, faculty member, or other individual wanting to file a grievance with respect to any aspect of an activity sponsored or cosponsored by The University of Tennessee College of Pharmacy may contact the Associate Dean for Continuing Education in writing at gfarr@utasip.com. The grievance will be reviewed and a response will be returned within 45 days of receiving the written statement. If not satisfied, an appeal to the Dean of the College of Pharmacy can be made for a second level review.


The following is an enduring roundtable CPE activity designed to help you gauge your basic knowledge of hyperkalemia and then direct you to areas you may need to focus on. It consists of 3 sections: an unaccredited pre-test, an interactive case study, and a CPE post-test, and evaluation. All 3 sections must be completed to receive CPE credit. A statement of credit will be available online immediately following successful completion of the activity.


Please ensure the computer you plan to use meets the following minimum requirements:

  • Operating System: Windows 98 or higher & Macintosh 2.2 or higher
  • Internet Browser (Mac &/Windows): Internet Explorer 6.0 or higher, Google Chrome, Safari 5.0.6 or higher, Firefox 3.0.3 or higher & Opera 5 or higher
  • Broadband Internet connection: Cable, High-speed DSL & any other medium that is internet accessible
  • Peripherals: Computer speakers or headphones
  • Monitor Screen Resolution: 320 x 480 or higher
  • Media Viewing Requirements: Adobe Reader, Microsoft Powerpoint, Flash Player & HTML5


  • Preassessment

  • Managing Hyperkalemia in the Inpatient Setting:
    Evolving Strategies to Ensure Optimal Patient Outcomes

    Faculty Panel

  • Postassessment and Evaluation

What you are about to see is a previously filmed roundtable discussion. Please note that only
"home study" credit will be awarded for participating in this archived presentation.

No "live" credits are available.