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Finding the Recipe for Success in Diabetes: Achieving Targets with Oral Combination Therapy

This educational activity is sponsored by Postgraduate Healthcare Education, LLC (PHE)
and supported by an educational grant from Merck.


Joshua J. Neumiller, PharmD, CDE, FAADE, FASCP
Vice-Chair & Allen I. White Distinguished Associate Professor
Department of Pharmacotherapy
College of Pharmacy and Pharmaceutical Sciences
Washington State University

Medical Writer
Laura K. Stinson, PharmD
Academic Detailing Pharmacist
University of Kentucky
Medical Writer and Education Consultant
The Stinson Pen, LLC


Joshua J. Neumiller, PharmD, CDE, FAADE, FASCP has no actual or potential conflicts of interest in relation to this program.

The clinical reviewer, Katelyn O’Brien, PharmD, has no actual or potential conflicts of interest in relation to this program.

Susanne Batesko, RN, BSN, and Robin Carrino, as well as the planners, managers, and other individuals, not previously disclosed, who are in a position to control the content of Postgraduate Healthcare Education (PHE) continuing education activities hereby state that they have no relevant conflicts of interest and no financial relationships or relationships to products or devices during the past 12 months to disclose in relation to this activity. PHE is committed to providing participants with a quality learning experience and to improve clinical outcomes without promoting the financial interests of a proprietary business.


acpePostgraduate Healthcare Education, LLC is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
UAN: 0430-0000-20-011-H01-P 
Credits: 2.0 hours (0.20 ceu)

Type of Activity: Knowledge 

Media: Internet

Fee Information: There is no fee for this educational activity.

Estimated time to complete activity: 120 minutes


 February 18, 2020


 February 18, 2021 


This accredited activity has been designed for pharmacists.

How to Earn Credit

During the period February 18, 2020 to February 18, 2021, participants must 1) read the learning objectives and faculty disclosures; 2) view the educational activity; and 3) complete the posttest and evaluation form directly after the activity within a maximum of 60 days of participating in the activity. To answer the questions, click on your selected choice for each answer then proceed to the next question. Once completed, click on the Grade Exam button at the bottom of the page. Your posttest will automatically be graded. If you successfully complete the posttest (score of 70% or higher), your statement of participation will be made available immediately. Click on the View Statement of Participation link and print the statement for your records. If you receive a score lower than 70%, you will receive a message notifying you that you did not pass the posttest. You will have 2 opportunities to pass the posttest. To receive Credit, you must provide your date of birth and NABP number. All Credit information will be uploaded into CPE monitor within 30 days.


The goal of this program is to increase pharmacist knowledge regarding combination therapy using glucose-lowering medications from the DPP-4 inhibitor and SGLT2 inhibitor medication classes. Learners will understand guidelines recommendations for use of these agents, safety and efficacy data on their combined use with other glucose-lowering agents in clinical trials, and how fixed-dose combinations can be used to address adherence issues. After participation in this initiative, pharmacists will be better able to recommend treatment that will help patients overcome barriers to achieving individualized glycemic goals and improved outcomes.


Upon completion of this program, participants should be better able to:

  1. Examine guideline recommendations for use of combination therapy in type 2 diabetes and explore patient- and medication-related factors that influence agent selection;
  2. Discuss the role of DPP-4 inhibitors and SGLT-2 inhibitors as components of combination therapy in patients with type 2 diabetes;
  3. Review clinical trial data related to combination glucose-lowering therapy with DPP-4 inhibitors and SGLT-2 inhibitors; and
  4. Describe the consequences of medication non-adherence in type 2 diabetes and how fixed-dose combination products can be used to simplify medication taking in patients with type 2 diabetes.


Please ensure the computer system you plan to use meets the following minimum requirements:

  • Operating System: Windows 98 or higher & Macintosh 2.2 or higher
  • Internet Browser (Mac &/ Windows): Internet Explorer 6.0 or higher, Google Chrome, Safari 5.0.6 or higher, Firefox 3.0.3 or higher & Opera 5 or higher
  • Broadband Internet connection: Cable, High-speed DSL & any other medium that is internet accessible
  • Peripherals: Computer speakers or headphones
  • Monitor Screen Resolution: 320 x 480 or higher
  • Media Viewing Requirements: Adobe Reader, Microsoft PowerPoint, Flash Player & HTML5

Disclosure of Unlabeled Use and Disclaimer:

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Postgraduate Healthcare Education, LLC or Merck. Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions, and possible contraindications on dangers in use, (review of any applicable manufacturer's product information) and comparison with recommendations of other authorities.

The author, sponsor, and publisher of this continuing education activity have made all reasonable efforts to ensure that all information contained herein is accurate in accordance with the latest available scientific knowledge at the time of acceptance for publication. However, because information regarding drugs (their administration, dosages, contraindications, adverse reactions, interactions, special warnings, precautions, etc.) is subject to constant change, the reader is advised to check the manufacturer's package insert for information concerning recommended dosages and potential problems and cautions prior to dispensing or administering the drug. Special precautions should be taken when a drug is new, or highly toxic, or is unfamiliar to the dispenser or administrant. This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the U.S. Food and Drug Administration (FDA). Neither the publisher nor sponsor promotes the use of any agent outside of approved labeling. Statements made in this activity have not been evaluated by the FDA.