Nephrology Rounds: The Role of the Pharmacist in the Management of Anemia in Chronic Kidney Disease Patients
Provided by American Academy of CME, Inc.
This educational activity is supported by an educational grant from Akebia Therapeutics.
April 30, 2020
April 30, 2021
Estimated time to complete activity
Anemia is common in patients with chronic kidney disease (CKD). Historically, treatment has consisted of oral or intravenous (IV) iron supplementation or the use of erythropoiesis stimulating agents (ESAs). Each of these approaches has its limitations and neither address the underlying cause of anemia. Advances in understanding the pathophysiological drivers of anemia in patients with CKD are informing the development of new approaches to correcting anemia in CKD, including stabilizing hypoxia inducible factor (HIF) by inhibiting prolyl hydroxylase (PH). Several HIF-stabilizers are currently being investigated and the role of these agents in treating anemia in patients with CKD is being shaped as data from clinical data are released.
As part of the interprofessional CKD healthcare team, pharmacists play a key role in comprehensive medication management as well as educating their colleagues about potential new treatments and implications for patient care.
Calvin J. Meaney, PharmD, BCPS
Clinical Associate Professor
University at Buffalo School of Pharmacy & Pharmaceutical Sciences
This activity has been developed for the pharmacist engaged in the care of patients with chronic kidney disease.
After attending this educational activity, learners should be better able to:
- Review the causes and underlying pathophysiology of anemia in patients with CKD
- Assess current options for treating anemia in patients with CKD
- Describe the role of hypoxia inducible factor (HIF) in CKD anemia and the rationale for developing therapy that targets prolyl hydroxylase (PH)
- Evaluate emerging data and clinical implications of HIF stabilization/PH inhibition as a strategy to address anemia in CKD
- Review the pharmacist role in patient care and management of therapy options
Accreditation and Credit Designation
In support of improving patient care, this activity has been planned and implemented by American Academy of CME, Inc. American Academy of CME, Inc. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
This activity provides 1.5 ACPE contact hours (0.15 CEUs) of continuing education credit. Universal Activity Number JA4008191-0000-20-005-H01-P, Application
According to the disclosure policy of the Academy, all faculty, planning committee members, editors, managers and other individuals who are able to control content are required to disclose any relevant relationships with any commercial interests related to this activity. The existence of these interests or relationships is not viewed as implying bias or decreasing the value of the presentation. All educational materials are reviewed for fair balance, scientific objectivity and levels of evidence.
Calvin J. Meaney, PharmD, BCPS
No relevant financial relationships with any commercial interests.
John JD Juchniewicz, MCIS, CHCP, Edward Moylan, RPh, Wendy Gloffke, PhD and Paul Miniter, MS - No relevant financial relationships with any commercial interests.
Philip Coco, PharmD has no relevant financial relationships with any commercial interests.
This activity will review off-label or investigational information.
The opinions expressed in this educational activity are those of the faculty, and do not represent those of the Academy. This activity is intended as a supplement to existing knowledge, published information, and practice guidelines. Learners should appraise the information presented critically and draw conclusions only after careful consideration of all available scientific information.
Method of Participation
There are no fees to participate in the activity. Participants must review the activity information including the learning objectives and disclosure statements, as well as the content of the activity. To receive CPE credit for your participation, please complete the post-test (achieving a passing grade of 70% or greater), and program evaluation. Your certificate can be printed immediately. For pharmacists, a statement of credit will be issued through CPE Monitor in 6-8 weeks. Only pharmacist learners who provided valid NABP e-Profile ID numbers and month and day of birth (MMDD) will be submitted to CPE Monitor for official record of credit.
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