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Optimizing Asparaginase Therapy for Acute Lymphoblastic Leukemia: Oncology Pharmacist and Nurse Perspectives
Jointly Provided by Postgraduate Healthcare Education, LLC (PHE) and Postgraduate Institute for Medicine (PIM).
This activity is supported by an independent educational grant from Jazz Pharmaceuticals.
FACULTY
Ryan J. Daley, PharmD, BCOP
Clinical Pharmacy Specialist, Leukemia
Memorial Sloan Kettering Cancer Center
New York, NY
Katherine L. Byar, MSN, ANP, BC, BMTCN
Nurse Practitioner, Hematologic Malignancy
Nebraska Medicine
Fred & Pamela Buffett Cancer Center
Omaha, NE
FINANCIAL DISCLOSURE
Dr. Daley has disclosed that he has received consulting fees for Da Volterra (Paris, France) and has an ownership interest (less than 5%) in Aprea Therapeutics, Inc.
Ms. Byar has disclosed that she has no relevant affiliations or financial relationships with a commercial interest to disclose.
The clinical reviewer, Lisa Holle, PharmD, BCOP, FHOPA, FISOPP, has disclosed that she has no relevant affiliations or financial relationships with a commercial interest to disclose.
The writer, Thomas Cook, RPh, PhD, has disclosed that he has no actual or potential conflicts of interest in relation to this program.
Susanne Batesko, RN, BSN, Robin Soboti, RPh, and Susan R. Grady, MSN, RN as well as the planners, managers, and other individuals, not previously disclosed, who are in a position to control the content of Postgraduate Healthcare Education (PHE) continuing education (CE) activities hereby state that they have no relevant conflicts of interest and no financial relationships or relationships to products or devices during the past 12 months to disclose in relation to this activity. PHE is committed to providing participants with a quality learning experience and to improve clinical outcomes without promoting the financial interests of a proprietary business.
The PIM planners and others have nothing to disclose.
Postgraduate Institute for Medicine (PIM) requires faculty, planners, and others in control of educational content to disclose all their financial relationships with ineligible companies. All identified conflicts of interest (COI) are thoroughly vetted and mitigated according to PIM policy. PIM is committed to providing its learners with high quality accredited continuing education activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.
All relevant financial relationships have been mitigated
ACCREDITATION STATEMENTS
PHARMACY
Postgraduate Healthcare Education, LLC is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
UAN: 0430-9999-22-067-H01-P
Credits: 2.0 hours (0.20 ceu)
Type of Activity: Application
Media: Internet
Fee Information: There is no fee for this educational activity.
Estimated time to complete activity: 120 minutes
Joint Accreditation Statement
In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and Postgraduate Healthcare Education. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Continuing Nursing Education
The maximum number of hours awarded for this Continuing Nursing Education activity is 2.0 contact hours. Designated for 0.75 contact hours of pharmacotherapy credit for Advanced Practice Registered Nurses.
Published
August 26, 2022
Reviewed: November 26, 2022
See UPDATE at the end of the monograph.
Expires
February 26, 2023
TARGET AUDIENCE
Oncology Pharmacists, Nurses & Nurse Practitioners
HOW TO OBTAIN CREDIT
During the period August 26, 2022 to February 26, 2023, participants must 1) read the learning objectives and faculty disclosures; 2) view the educational activity; and 3) complete the posttest and evaluation form directly after the activity within a maximum of 60 days of participating in the activity. To answer the questions, click on your selected choice for each answer then proceed to the next question. Once completed, click on the Grade Exam button at the bottom of the page. Your posttest will automatically be graded. If you successfully complete the posttest (score of 70% or higher), your statement of participation will be made available immediately. Click on the View Statement of Participation link and print the statement for your records. If you receive a score lower than 70%, you will receive a message notifying you that you did not pass the posttest. You will have 2 opportunities to pass the posttest. To receive Credit, you must provide your date of birth and NABP number. All Credit information will be uploaded into CPE monitor within 30 days.
SPECIAL NOTE
Learners claiming ACPE- or ANCC-credit for this activity will be invited to participate in a small group virtual Q&A session (PowerUp LIVE) with the faculty. Each PowerUp LIVE session is ACPE- and ANCC-accredited for 0.5 credit hours. Registration will be required.
Goal
Provide oncology pharmacists and nurses with enhanced knowledge and competence on the use of asparaginase for the treatment of acute lymphoblastic leukemia including types of approved agents, efficacy, toxicity, and approaches for adverse event prevention and management, all of which will help to improve patient outcomes.
EDUCATIONAL OBJECTIVES
At the conclusion of the activities, the learner will be able to:
- Explain the rationale for use of asparaginase in the treatment of acute lymphoblastic leukemia
- Recognize the differences among available forms of asparaginase
- Describe the basis for selecting the best type of asparaginase based on patient-specific factors, and the optimal dose and route of administration
- Formulate approaches for identifying and mitigating toxicities associated with asparaginase therapy to optimize treatment outcomes
REQUIRED COMPUTER HARDWARE/SOFTWARE
Please ensure the computer system you plan to use meets the following minimum requirements:
- Operating System: Windows 98 or higher & Macintosh 2.2 or higher
- Internet Browser (Mac & Windows): Internet Explorer 6.0 or higher, Google Chrome, Safari 5.0.6 or higher, Firefox 3.0.3 or higher, & Opera 5 or higher
- Broadband Internet connection: Cable, High-speed DSL & any other medium that is internet accessible
- Peripherals: Computer speakers or headphones
- Monitor Screen Resolution: 320 x 480 or higher
- Media Viewing Requirements: Adobe Reader, Microsoft PowerPoint, Flash Player & HTML5
Disclosure of Unlabeled Use and Disclaimer
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Postgraduate Healthcare Education, LLC, Postgraduate Institute for Medicine (PIM), or Jazz Pharmaceuticals. Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions, and possible contraindications on dangers in use, (review of any applicable manufacturer's product information) and comparison with recommendations of other authorities.
The author, sponsor, and publisher of this continuing education activity have made all reasonable efforts to ensure that all information contained herein is accurate in accordance with the latest available scientific knowledge at the time of acceptance for publication. However, because information regarding drugs (their administration, dosages, contraindications, adverse reactions, interactions, special warnings, precautions, etc.) is subject to constant change, the reader is advised to check the manufacturer's package insert for information concerning recommended dosages and potential problems and cautions prior to dispensing or administering the drug. Special precautions should be taken when a drug is new, or highly toxic, or is unfamiliar to the dispenser or administrant. This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the U.S. Food and Drug Administration (FDA). Neither the publisher nor sponsor promotes the use of any agent outside of approved labeling. Statements made in this activity have not been evaluated by the FDA.
