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1. The U.S. Food and Drug Administration (FDA) Risk Evaluation and Mitigation Strategy (REMS) document entitled a Blueprint for Prescriber Education for Extended-Release and Long-Acting Opioid Analgesics, released in 2012, was a

A. Set of guidelines to help guide the provider assess the benefits and the risks of prescribing chronic opioid therapy (COT) B. Set of rules to help guide the provider when prescribing COT C. Set of regulations to help guide the provider when prescribing COT D. Set of legislation to help guide the provider when prescribing COT

2. The FDA REMS document from 2012 endorses which of the following, as it relates to COT:

A. Use of screening tools for aberrant drug seeking behavior associated with COT B. Use of urine drug monitoring (UDM) when prescribing COT C. USE of patient and prescriber agreements (PPAs) when prescribing COT D. All of the above

3. The use of Prescription Drug Monitoring Program (PDMP) reports helps to identify those patients that may be exhibiting aberrant drug-seeking behavior by providing which of the following:

A. A list of prescribers that have been prescribing a patient opiates B. A list of chemicals that are present in a patient's body C. A document that is signed by both the patient and provider that guides therapy D. Data to the local Drug Enforcement Administration (DEA) office

4. Which of the following is not a standard test given to patients to screen for risk for opioid misuse:

A. Opioid Risk Tool (ORT) B. Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) C. Current Opioid Misuse Measure (COMM) D. PPA

5. Which of the following contribute to the complexity of prescribing COT:

A. Patient expectations of COT therapy B. Providers' emotional reactions C. Public health issues D. All of the above

6. Which of the following is the appropriate conversion morphine equivalent dose (MED) for hydromorphone:

A. 1 MED B. 1.5 MED C. 3 MED D. 5 MED

7. Which is the appropriate equianalgesic conversion MED for methadone

A. 1 MED B. 1.5 MED C. 3 MED D. None of the above

8. Which of the following is a dose of morphine that is associated with a significantly higher risk of accidental overdose:

A. 70 MED B. 80 MED C. 90 MED D. 100 MED

9. If a patient is exhibiting aberrant drug seeking-behavior by repeatedly claiming their opioid prescription has been lost and calling for early refills, which of the following is the best course of action:

A. Provide the local DEA office with the patient's name B. When counseling the patient, keep the discussion solely on the patient safety C. Provide the local Board of Pharmacy with the patient's name D. When counseling the patient, focus solely on the patient's actions

10. When dispensing a COT medication, which of the following can help the pharmacist make the best decision:

A. Use the same tools and thought process as with any other chronic medication B. Use a Universal Precautions model when counseling your patient C. Use a T.H.I.N.K. model when counseling your patient D. All of the above