1. Definitions of multi-drug resistant bacteria:

2. What is the mechanism of resistance of vancomycin-resistant enterococci?

3. A 67-year old woman with a history of smoking is admitted from the ED for rapidly progressing pneumonia. Despite therapy, she exhibits worsening signs and is transferred to the ICU. P. aeruginosa is isolated from sputum specimens. What therapy would you select for her?

4. Ceftolozane, the new cephalosporin in the combination of ceftolozane-tazobactam, is distinguished from other cephalosporins by its activity against which of the following?

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