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1. When can Zika virus be definitively diagnosed by urine reverse transcriptase polymerase chain reaction?

A. 15 days after the patient becomes symptomatic B. <14 days after onset of symptoms, along with a positive serologic test C. <14 days after onset of symptoms, along with a negative serologic test D. A definitive diagnosis cannot be made

2. Which statement about male-to-female sexual transmission is true?

A. It is less common than female-to-male transmission B. It is not yet known whether it is more or less common than female-to-male transmission C. It is equally as common as female-to-male transmission D. Male-to-female transmission does not occur

3. Ocular effects of Zika virus include which of the following?

A. Ocular lesions B. Conjunctivitis C. Both a and b D. Zika virus has no ocular effects

4. When can Zika virus be sexually transmitted?

A. Only during an active infection B. Before symptoms present C. Only after the carrier is symptomatic D. It is not known whether Zika virus can be sexually transmitted

5. Which of the following is a prevention method for sexually transmitted Zika virus?

A. The use of dental dams B. Abstinence C. Protected sex for 6 months if diagnosed male partner lives in an area with Zika virus D. All of the above

6. Which statement characterizes Zika virus?

A. It is related to the influenza virus B. It is an arbovirus in the Flavivirus genus of the Flaviviridae family C. It is a bacterium D. None of the above

7. Zika has been detectable for up to 6 months in which type of bodily fluid?

A. Saliva B. Vaginal secretions C. Semen D. Sweat

8. Which of these terms is applicable to Zika virus transmitted via a mosquito bite?

A. Maternal transmission B. Blood-borne transmission C. Vector-borne transmission D. Sexual transmission

9. Which statement regarding microcephaly in babies born to Zika-infected mothers is true?

A. All such babies will have microcephaly B. Only babies born in Brazil will have microcephaly C. Only babies born in South America will have microcephaly D. Only some babies will have microcephaly

10. Which pregnancy trimester poses the greatest risk of Zika-related abnormalities in a fetus?

A. 1st trimester B. 2nd trimester C. 3rd trimester D. All of the above

11. Which symptom is not characteristic of Zika infection?

A. Low-grade fever B. Muscle pain C. Maculopapular pruritic rash D. All of the above are characteristic of Zika infection

12. When should nonsteroidal anti-inflammatory drugs and aspirin be implemented for symptoms of Zika virus?

A. Immediately B. When dengue has been ruled out C. Never D. On a case-by-case basis

13. By what time period does immunoglobulin M develop?

A. Week 4 B. Week 1 C. Month 1 D. None—IgM never develops

14. The clinical presentation of a Zika infection is similar to that of which other disease?

A. Ebola virus B. Dengue C. Chikungunya D. B and C

15. Pharmacists counsel patients about Zika infections by reviewing which of the following?

A. Preventive measures B. Signs and symptoms C. Risk of infection D. All of the above

16. Once a mosquito acquires Zika virus, for up to how long can it be infective?

A. 10 days B. 20 days C. 30 days D. 60 days

17. Which statement about Zika infection is true?

A. Every person with Zika virus will develop an infection B. Not all people with Zika virus will develop an infection C. All women with Zika virus will develop an infection D. All men with Zika virus will develop an infection

18. What sort of care is required for Zika patients with Guillain-Barré syndrome?

A. Hospitalization B. Supportive care C. Neither A nor B D. Both A and B

19. Which statement about testing is true for a pregnant woman who has recently traveled to an area with Zika virus?

A. Perform fetal ultrasound if her Zika test is negative B. Do not perform fetal ultrasound if her Zika test is negative C. Do not perform fetal ultrasound if her Zika test is positive D. Do not perform a Zika test

20. What type of care is appropriate for a pregnant woman residing in an area with Zika virus who has no clinical illness and tests negative for the virus?

A. Zika virus retesting in 2nd trimester B. Routine prenatal care C. Ultrasound at 18-20 weeks' gestation D. A and C