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1. Which one of the following medications can produce arrhythmias and would warrant ordering an EKG in a patient with prior history of QTc prolongation?

A. Methadone B. Buprenorphine C. Buprenorphine/Naloxone D. Naltrexone

2. What is the maximum Day 1 dose of methadone for a healthy male?

A. 5 mg B. 15 mg C. 30 mg D. 40 mg

3. When should buprenorphine/naloxone be initiated?

A. Patient is exhibiting respiratory depression due to opioid toxicity B. Patient is symptom free after opioid withdrawal and toxicity C. Patient is experiencing mild opioid withdrawal symptoms with COWS of 5 D. Patient is experiencing mild to moderate opioid withdrawal symptoms with COWS of 12

4. A patient who has been abusing heroin should be counseled to remain opioid-free for at least how many days before initiating naltrexone?

A. 1 day B. 3 days C. 7 days D. 14 days

5. Which one of the following patient variables may necessitate a longer needle when administering long-acting naltrexone injectable?

A. Obesity B. Hepatitis C. Renal impairment D. History of allergic reaction

6. A patient with history of opioid use disorder is being treated with naltrexone and is experiencing side effects. Which one of the following is necessary?

A. Naltrexone must be slowly tapered over 2 weeks before starting buprenorphine/naloxone B. Naltrexone must be slowly tapered over 4 weeks before starting buprenorphine/naloxone C. Buprenorphine/naloxone should be started lower at a lower dose than for opioid dependent patients D. Buprenorphine/naloxone would be contraindicated in this patient and should be not initiated

7. A buprenorphine urine drug screen that includes synthetic opioids can routinely be used to determine which one of the following?

A. Adherence B. Efficacy C. Side effects D. Drug-drug interactions

8. A patient presents to a local pharmacy with a prescription for buprenorphine/naloxone sublingual tablets and wants to know why naloxone is included with this medication. Which one of the following is correct?

A. Naloxone is included to prevent opioid overdose B. Naloxone is included to reduce buprenorphine-associated side effects C. Naloxone is included to decrease drug-drug interactions D. Naloxone is included to prevent diversion

9. A patient is being treated with methadone for opioid use disorder and is stable. She discovers that she is 10 weeks pregnant. Which one of the following is correct?

A. Methadone should be discontinued immediately B. Methadone should be tapered over 4 weeks C. The methadone dose may need to be increased as the pregnancy progresses D. Methadone should be slowly cross-tapered with naltrexone over 8 weeks

10. A patient is admitted to a local hospital after experiencing a motor vehicle accident. The patient has a history of opioid use disorder and is being treated with buprenorphine/naloxone. The admitting physician is not DATA waivered to prescribe buprenorphine/naloxone. Which one of the following is required?

A. Buprenorphine/naloxone must be discontinued B. The treating physician can continue to prescribe during hospitalization since patient was admitted for trauma C. The treating physician must find a DATA waivered hospitalist to prescribe buprenorphine/naloxone D. The treating physician can prescribe buprenorphine/naloxone during the hospitalization and upon discharge