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1. Which of the following is NOT a risk factor for acute and long-term rejection in patients with renal transplants?

A. Pregnancy B. Older age C. Nonadherence D. Nonwhite race E. Unsure

2. Which of the following leads to sensitization, or antibody formation against non-self human antigen?

A. Blood transfusions B. Nonadherence C. Vaccinations D. Infection E. Unsure

3. An 18-year-old girl who is several years post-renal transplant has not been taking her antirejection drugs as directed over the past 3 months. While she has some sociodemographic risk factors that have been associated with nonadherence, she insists that side effects are causing her concerns and that is why she is skipping doses. If this is in fact the case, which of the following sets of potential problems would be most likely in this patient?

A. Diabetes, infections, and kidney pain B. Kidney pain, rhabdomyolysis, and diuresis C. Diuresis, fatigue, and gastrointestinal complications D. Gastrointestinal complications, symptoms of diabetes, and infections E. Unsure

4. When the U.S. Food and Drug Administration held a public forum for patients and caregivers on the impact of transplant on their daily lives, what did patients report as a challenge with regard to immunosuppressant medications?

A. Too many medication options B. Problems obtaining medications C. Intolerability of immunosuppressants D. Cost of medications E. Unsure

5. According to the meta-analysis by Butler and colleagues, what percentage of graft loss was associated with prior nonadherence?

A. 36% B. 7% C. 23% D. 52% E. Unsure

6. Which of the following is an example of a modifiable risk factor for nonadherence?

A. Age B. Reduced self-efficacy C. Time since transplant D. Race E. Unsure

7. What was the primary significant result of the TAKE-IT trial in adolescents and young adults?

A. Improved tacrolimus trough levels in the intervention arm B. Decreased acute rejection in the intervention arm C. Intervention patients had improved adherence as compared with controls D. Control and intervention patients had improved adherence E. Unsure

8. According to the data published by Reese and colleagues, adherence was the highest in which arm of their study of technology?

A. Patients who had customized reminders and wireless pill bottle B. Patients who had customized reminders and provider notification if adherence was less than 90% and wireless pill bottle C. Patients who had a wireless pill bottle alone D. No group was better than the others E. Unsure

9. By implementing a specialty pharmacy service with medication delivery, refill reminders, and adherence screening and intervention, Tschida and colleagues found a decrease in what outcome?

A. Total health care costs B. Adherence rates C. Rejection rates D. Medication cost E. Unsure

10. A 57-year-old man received a renal transplant 8 months ago. Immunosuppressants are being used to prevent rejection and the patient has been adherent to the regimen. The patient's blood pressure has been rising gradually, and his physician has now added hypertension as a diagnosis. Which of the following statements best describes the likely etiology of the increase in blood pressure?

A. The increase is most likely the result of adverse drug effects. B. The increase is most likely the result of underlying pathology. C. The increase is most likely an underlying condition, with possible exacerbation by immunosuppressant drugs. D. The increase is likely the result of long-term rejection of the new kidney. E. Unsure

Evaluation Questions

11. How confident are you in your decision about treatment for your 18 year-old female patient in the question above?

A. Not at all confident B. Somewhat confident C. Confident D. Highly confident

12. How confident are you in your decision about treatment for your 57 year-old male patient in the question above?

A. Not at all confident B. Somewhat confident C. Confident D. Highly Confident

Maintenance is scheduled for 8/7/2023 7:00 AM EST - 8:00 AM EST.

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1. Which of the following is NOT a risk factor for acute and long-term rejection in patients with renal transplants?

2. Which of the following leads to sensitization, or antibody formation against non-self human antigen?

4. When the U.S. Food and Drug Administration held a public forum for patients and caregivers on the impact of transplant on their daily lives, what did patients report as a challenge with regard to immunosuppressant medications?

5. According to the meta-analysis by Butler and colleagues, what percentage of graft loss was associated with prior nonadherence?

6. Which of the following is an example of a modifiable risk factor for nonadherence?

7. What was the primary significant result of the TAKE-IT trial in adolescents and young adults?

8. According to the data published by Reese and colleagues, adherence was the highest in which arm of their study of technology?

9. By implementing a specialty pharmacy service with medication delivery, refill reminders, and adherence screening and intervention, Tschida and colleagues found a decrease in what outcome?

Evaluation Questions

11. How confident are you in your decision about treatment for your 18 year-old female patient in the question above?

12. How confident are you in your decision about treatment for your 57 year-old male patient in the question above?

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Maintenance is scheduled for 8/7/2023 7:00 AM EST - 8:00 AM EST.

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1. Which of the following is NOT a risk factor for acute and long-term rejection in patients with renal transplants?

2. Which of the following leads to sensitization, or antibody formation against non-self human antigen?

4. When the U.S. Food and Drug Administration held a public forum for patients and caregivers on the impact of transplant on their daily lives, what did patients report as a challenge with regard to immunosuppressant medications?

5. According to the meta-analysis by Butler and colleagues, what percentage of graft loss was associated with prior nonadherence?

6. Which of the following is an example of a modifiable risk factor for nonadherence?

7. What was the primary significant result of the TAKE-IT trial in adolescents and young adults?

8. According to the data published by Reese and colleagues, adherence was the highest in which arm of their study of technology?

9. By implementing a specialty pharmacy service with medication delivery, refill reminders, and adherence screening and intervention, Tschida and colleagues found a decrease in what outcome?

Evaluation Questions

11. How confident are you in your decision about treatment for your 18 year-old female patient in the question above?

12. How confident are you in your decision about treatment for your 57 year-old male patient in the question above?

« Return to Activity

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