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1. Which of the following does NOT describe a physiologic change that occurs during pregnancy that impacts drug distribution:

A. Weight gain B. Decrease in plasma protein concentration C. Increase in blood flow to the liver and kidneys D. Increase in volume of plasma E. Unsure

2. Which of the following nonpharmacologic management strategies is considered safe throughout pregnancy, regardless of which trimester the patient is in:

A. Transcutaneous electrical nerve stimulation B. Water therapy C. Massage D. Chiropractic care E. Unsure

3. Biofeedback is a nonpharmacologic, behavioral measure that may provide pain relief in pediatric patients. Which of the following definitions best describes biofeedback?

A. Transmission of small electrical impulses to the nerves via patches placed on the skin to block pain B. An altered state of consciousness that allows increased responsiveness to suggestions to allow for positive changes C. Use of electronic devices to monitor bodily functions, then teach patients how to consciously regulate those functions D. Therapy that allows patients to recognize negative ways of thinking so that they can be altered to improve feelings of anxiety and stress E. Unsure

4. Nonpharmacologic management is the preferred strategy for initial management of neonatal opioid withdrawal syndrome (NOWS). Which of the following describes a nonpharmacologic strategy that is recommended when managing a neonate with opioid withdrawal?

A. Providing a dark environment with minimal stimulation B. Swaddling the neonate C. Holding, cuddling, or rocking the infant to reduce stress D. All of the above describe nonpharmacologic strategies used to manage NOWS E. Unsure

5. The American College of Obstetricians and Gynecologists and the Academy of Breastfeeding Women recommend ________ first-line for management of pain in breastfeeding women?

A. Acetaminophen B. Ibuprofen C. Tramadol D. Morphine E. Unsure

6. A 6-year-old male with no other medical conditions is assessed, and determined to have moderate postoperative pain that has persisted despite treatment with ibuprofen. The attending physician would like to initiate an opioid to better address this child's pain. Which of the following would be the most reasonable opioid to initiate in this patient for acute pain management?

A. Morphine, immediate-release oral solution B. Morphine, intramuscular injection C. Oxycodone, extended-release oral tablet D. Fentanyl, intravenous infusion E. Unsure

7. All of the following describe potential adverse effects related to nonsteroidal anti-inflammatory drug (NSAID) use in older adults, EXCEPT?

A. Increased risk for gastrointestinal bleeding B. Cardiovascular toxicity C. Loss of blood pressure control D. Lack of anti-inflammatory action E. Unsure

8. Pain management can be complicated in palliative care patients due to:

A. Inability of the patient to request pain medication B. Provider fear of hastening death by administering high-dose opioids C. Inability to swallow due to weakness or sedation D. All of these factors can complicate pain management in palliative care patients E. Unsure

9. Which of the following agents does NOT have an active metabolite that can accumulate in patients with severe renal impairment?

A. Hydromorphone B. Fentanyl C. Morphine D. Oxycodone E. Unsure

10. Match the genotype of the OPRM1 gene with the correct expected outcome:

A. AA genotype – reduced pain relief from opioids B. GG genotype – increased pain relief from opioids C. GG genotype – reduced pain relief from opioids D. None of these are correct E. Unsure

Maintenance is scheduled for 05/16/2024 5:00 PM EST - 05/17/2024 5:00 AM EST.

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1. Which of the following does NOT describe a physiologic change that occurs during pregnancy that impacts drug distribution:

2. Which of the following nonpharmacologic management strategies is considered safe throughout pregnancy, regardless of which trimester the patient is in:

3. Biofeedback is a nonpharmacologic, behavioral measure that may provide pain relief in pediatric patients. Which of the following definitions best describes biofeedback?

4. Nonpharmacologic management is the preferred strategy for initial management of neonatal opioid withdrawal syndrome (NOWS). Which of the following describes a nonpharmacologic strategy that is recommended when managing a neonate with opioid withdrawal?

5. The American College of Obstetricians and Gynecologists and the Academy of Breastfeeding Women recommend ________ first-line for management of pain in breastfeeding women?

7. All of the following describe potential adverse effects related to nonsteroidal anti-inflammatory drug (NSAID) use in older adults, EXCEPT?

8. Pain management can be complicated in palliative care patients due to:

9. Which of the following agents does NOT have an active metabolite that can accumulate in patients with severe renal impairment?

10. Match the genotype of the OPRM1 gene with the correct expected outcome:

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Maintenance is scheduled for 05/16/2024 5:00 PM EST - 05/17/2024 5:00 AM EST.

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1. Which of the following does NOT describe a physiologic change that occurs during pregnancy that impacts drug distribution:

2. Which of the following nonpharmacologic management strategies is considered safe throughout pregnancy, regardless of which trimester the patient is in:

3. Biofeedback is a nonpharmacologic, behavioral measure that may provide pain relief in pediatric patients. Which of the following definitions best describes biofeedback?

4. Nonpharmacologic management is the preferred strategy for initial management of neonatal opioid withdrawal syndrome (NOWS). Which of the following describes a nonpharmacologic strategy that is recommended when managing a neonate with opioid withdrawal?

5. The American College of Obstetricians and Gynecologists and the Academy of Breastfeeding Women recommend ________ first-line for management of pain in breastfeeding women?

7. All of the following describe potential adverse effects related to nonsteroidal anti-inflammatory drug (NSAID) use in older adults, EXCEPT?

8. Pain management can be complicated in palliative care patients due to:

9. Which of the following agents does NOT have an active metabolite that can accumulate in patients with severe renal impairment?

10. Match the genotype of the OPRM1 gene with the correct expected outcome:

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