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1. What is the mechanism by which olaparib and rucaparib increase serum creatinine?

A. Inhibition of MATE transporters B. Renal tubule damage C. Tubular necrosis D. Nephrotic syndrome E. Unsure

2. Which of the following is a recommended antiemetic regimen for olaparib?

A. Ondansetron 4-8 mg with each olaparib dose (8-16 mg/day) B. Palonosetron 0.25 mg and dexamethasone 8 mg on Day 1 C. Dronabinol 2.5 mg 3 times a day as needed D. Prochlorperazine 5-10 mg with each olaparib dose (10-20 mg/day) E. Unsure

3. Which PARP inhibitor(s) has/have been approved by the United States Food and Drug Administration (FDA) for use in the first-line maintenance setting in newly diagnosed ovarian cancer?

A. Olaparib monotherapy and olaparib in combination with bevacizumab B. Olaparib monotherapy and niraparib C. Olaparib monotherapy, olaparib in combination with bevacizumab, and niraparib alone D. Olaparib monotherapy, niraparib, and rucaparib E. Unsure

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