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1. All of the following are important issues in study design and ultimate clinical utility for pharmacological agents used to treat acute severe hypertension with end-organ damage except:

A. Titratability B. Oral bioavailability C. Degree of reflex tachycardia D. Comorbidities

2. JW is a 56-year-old male presenting to the emergency department with chief complaint of left-sided weakness and difficulty speaking. Patient has a past medical history of hypertension and hyperlipidemia but takes no medications. Vital signs on admission include a blood pressure 225/111, HR 86 beats per minute, respiratory rate of 32 breaths per minute, and O2 sat of 96% on room air. A STAT head CT shows evidence of an acute intracerebral hemorrhage. Which of the following statements is correct?

A. JW's systolic blood pressure should be controlled to < 140 mmHg to decrease risk of hematoma expansion B. JW's systolic blood pressure should be controlled to < 220 mmHg to allow for autoregulation and increase cerebral perfusion pressure. C. JW's systolic blood pressure should be controlled to < 140 mmHg to decrease risk of acute kidney injury D. JW's systolic blood pressure should be controlled to < 220 mmHg to increase the chance of good functional outcomes.

3. After his CT scan, JW returns to the emergency department. His nurse measures a repeat blood pressure and informs you that the blood pressure is now 225/114 mmHg. Which of the following is the most appropriate anti-hypertensive agent to administer for acute blood pressure control?

A. Hydralazine 20 mg IV push x 1 B. Nitroglycerin continuous infusion started at 10 mcg/min C. Clevidipine continuous infusion started at 2 mg/hr D. Sodium nitroprusside 0.3 mcg/kg/min

4. Which of the following agents would be most appropriate to initiate in a patient presenting to your hospital with Acute Severe Hypertension (BP 210/118) manifesting as acute pulmonary edema due to acute heart failure exacerbation?

A. Esmolol intravenous bolus, followed by a 50-mcg/kg/minute infusion B. Clevidipine intravenous infusion started at 2mg/hr C. Hydralazine IV 5–10 mg every 4–6 hours D. Diltiazem intravenous bolus followed by 5 mg/hr infusion

5. Pharmacist involvement in care of patients who are critically ill or experiencing medical emergencies has been demonstrated to achieve which of the following:

A. Increased adherence with guidelines B. Reduction of adverse events C. Cost avoidance D. All of the above

Maintenance is scheduled for 8/7/2023 7:00 AM EST - 8:00 AM EST.

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1. All of the following are important issues in study design and ultimate clinical utility for pharmacological agents used to treat acute severe hypertension with end-organ damage except:

3. After his CT scan, JW returns to the emergency department. His nurse measures a repeat blood pressure and informs you that the blood pressure is now 225/114 mmHg. Which of the following is the most appropriate anti-hypertensive agent to administer for acute blood pressure control?

4. Which of the following agents would be most appropriate to initiate in a patient presenting to your hospital with Acute Severe Hypertension (BP 210/118) manifesting as acute pulmonary edema due to acute heart failure exacerbation?

5. Pharmacist involvement in care of patients who are critically ill or experiencing medical emergencies has been demonstrated to achieve which of the following:

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Maintenance is scheduled for 8/7/2023 7:00 AM EST - 8:00 AM EST.

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1. All of the following are important issues in study design and ultimate clinical utility for pharmacological agents used to treat acute severe hypertension with end-organ damage except:

3. After his CT scan, JW returns to the emergency department. His nurse measures a repeat blood pressure and informs you that the blood pressure is now 225/114 mmHg. Which of the following is the most appropriate anti-hypertensive agent to administer for acute blood pressure control?

4. Which of the following agents would be most appropriate to initiate in a patient presenting to your hospital with Acute Severe Hypertension (BP 210/118) manifesting as acute pulmonary edema due to acute heart failure exacerbation?

5. Pharmacist involvement in care of patients who are critically ill or experiencing medical emergencies has been demonstrated to achieve which of the following:

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