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New Directions in the Management of Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: Utilizing Immunotherapy to Improve Outcomes

This educational activity is sponsored by Postgraduate Healthcare Education, LLC (PHE) and supported by an educational grant from Merck & Co.


Kirollos S. Hanna, PharmD, BCPS, BCOP
Oncology Pharmacy Manager
M Health Fairview - Maple Grove
Assistant Professor of Pharmacy
Mayo Clinic College of Medicine
Rochester, Minnesota


Dr. Hanna has disclosed that he has served as a paid consultant for Abbvie, Astellas AstraZeneca, BeiGene, Bristol Myers Squibb, Rigel, and SeaGen; and has received fees for other non-CE services from Astellas. BeiGene, Bristol Myers Squibb, and SeaGen.

The clinical reviewer, Megan May, PharmD, BCOP, has disclosed that she has no actual or potential conflicts of interest in relation to this program.

Susanne Batesko, RN, BSN, Robin Soboti, RPh, and Susan R. Grady, MSN, RN, as well as the planners, managers, and other individuals, not previously disclosed, who are in a position to control the content of Postgraduate Healthcare Education (PHE) continuing education (CE) activities hereby state that they have no relevant conflicts of interest and no financial relationships or relationships to products or devices during the past 12 months to disclose in relation to this activity. PHE is committed to providing participants with a quality learning experience and to improve clinical outcomes without promoting the financial interests of a proprietary business.


acpePostgraduate Healthcare Education, LLC is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
UAN: 0430-0000-22-015-H01-P
Credits: 2.0 hour (0.2 ceu)

Type of Activity: Application
Media: Internet

Fee Information: There is no fee for this educational activity.
Estimated time to complete activity: 120 minutes


May 20, 2022


November 20, 2022


This accredited activity has been designed for oncology, managed care and specialty pharmacists.


During the period May 20, 2022 to November 20, 2022, participants must 1) read the learning objectives and faculty disclosures; 2) view the educational activity; and 3) complete the post-test and evaluation form directly after the activity within a maximum of 60 days of participating in the activity. To answer the questions, click on your selected choice for each answer then proceed to the next question. Once completed, click on the Grade Exam button at the bottom of the page. Your post-test will automatically be graded. If you successfully complete the post-test (score of 70% or higher), your statement of participation will be made available immediately. Click on the View Statement of Participation link and print the statement for your records. If you receive a score lower than 70%, you will receive a message notifying you that you did not pass the post-test. You will have 2 opportunities to pass the post-test. To receive Credit, you must provide your date of birth and NABP number. All Credit information will be uploaded into CPE monitor within 30 days.


Learners claiming ACPE-credit for this activity will be invited (by email in July or November 2022) to participate in a small group virtual Q&A session (PowerUp LIVE) with the faculty in August or December 2022. Each PowerUp LIVE session is ACPE-accredited for 0.5 credit hours. Participation in these sessions will be limited.


To educate oncology, managed care, and specialty pharmacists on how to optimally manage adult patients with recurrent or metastatic head and neck squamous cell carcinoma, including ensuring appropriate access to patient-specific immunotherapy treatments, developing optimal toxicity prevention and management, and providing enhanced pharmaceutical care thus leading to optimized outcomes.


Upon completion of this program, participants should be better able to:

  • Describe the efficacy and safety of immune checkpoint inhibitors for the treatment of recurrent or metastatic head and neck squamous cell carcinoma (HNSCC)
  • Discuss the role for immune checkpoint inhibitors as monotherapy and in combination with chemotherapy in recurrent or metastatic HNSCC
  • Formulate strategies to recognize and manage patients’ immune-related adverse events in recurrent or metastatic HNSCC treatment


Please ensure the computer system you plan to use meets the following minimum requirements:

  • Operating System: Windows 98 or higher & Macintosh 2.2 or higher
  • Internet Browser (Mac & Windows): Internet Explorer 6.0 or higher, Google Chrome, Safari 5.0.6 or higher, Firefox 3.0.3 or higher, & Opera 5 or higher
  • Broadband Internet connection: Cable, High-speed DSL & any other medium that is internet accessible
  • Peripherals: Computer speakers or headphones
  • Monitor Screen Resolution: 320 x 480 or higher
  • Media Viewing Requirements: Adobe Reader, Microsoft PowerPoint, Flash Player & HTML5

Disclosure of Unlabeled Use and Disclaimer

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Postgraduate Healthcare Education, LLC, or Merck & Co. Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions, and possible contraindications on dangers in use, (review of any applicable manufacturer's product information) and comparison with recommendations of other authorities.

The author, sponsor, and publisher of this continuing education activity have made all reasonable efforts to ensure that all information contained herein is accurate in accordance with the latest available scientific knowledge at the time of acceptance for publication. However, because information regarding drugs (their administration, dosages, contraindications, adverse reactions, interactions, special warnings, precautions, etc.) is subject to constant change, the reader is advised to check the manufacturer's package insert for information concerning recommended dosages and potential problems and cautions prior to dispensing or administering the drug. Special precautions should be taken when a drug is new, or highly toxic, or is unfamiliar to the dispenser or administrant. This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the U.S. Food and Drug Administration (FDA). Neither the publisher nor sponsor promotes the use of any agent outside of approved labeling. Statements made in this monograph have not been evaluated by the FDA.