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1. Constipation is a problem that affects:

A. mainly older women and patients in long-term care facilities B. mainly men age 65 and over C. more than one-quarter of the U.S. adult population D. about half of the U.S. adult population E. Unsure

2. As defined by the Rome IV criteria, CIC or "functional constipation" is:

A. a distinctly separate entity from irritable bowel syndrome with constipation (IBS-C) B. different from IBS-C in terms of symptom presentation, although treatments are similar C. overlapping with CIC in terms of both symptom presentation and treatments D. no longer defined under the Rome IV criteria E. Unsure

3. The most common mechanism of chronic constipation is:

A. Normal gastrointestinal (GI) motility and hard stool B. Slow transit due to decreased GI motility C. Outlet dysfunction due to anal sphincter or intestinal anomalies D. Infrequent voiding due to poor toileting habits E. Unsure

4. Which of the following agents are defined as stimulant laxatives?

A. polyethylene glycol B. senna C. bisacodyl D. both B and C E. Unsure

5. A physician in your practice setting says he is prescribing a constipation therapy for a patient and asks you which guanylate cyclase-C agonist is on formulary. The agents in this category are:

A. linaclotide and plecanatide B. lubiprostone and linaclotide C. prucalopride and plecanatide D. all of the above E. Unsure

6. The 5 HT4 receptor agonists currently approved by the FDA for the treatment of adults with constipation are:

A. prucalopride only B. prucalopride and tegaserod C. cisapride and tegaserod D. none of the above E. Unsure

7. A patient in your community pharmacy wants to know if he can take more stool softener (docusate) because his usual dose (100 mg each morning) does not seem to help his "ongoing constipation problem." The most practical approach is:

A. He should feel free to increase the dose to 300 mg (3 docusate tablets) per day according to the labeling, since docusate has been shown to be effective for chronic constipation. B. He might want to try a rectally administered form of docusate for a while until the constipation clears up. C. Since docusate has not been shown to be effective for chronic constipation, you recommend an OTC stimulant laxative (no longer than 7 days) and to follow up with his doctor if he does not get relief. D. He should consult his physician immediately for a prescription constipation therapy. E. Unsure

8. Which of the following statements is true regarding constipation in the hospital setting?

A. Constipation occurs secondary to immobility, low food intake, and dehydration. B. Constipation is a common primary diagnosis in hospitalized patients. C. Agents such as stool softeners are often routinely overused in hospital settings. D. all of the above E. Unsure

9. You are asked to recommend medications for an 83-year-old woman who is being discharged home from a long-term care facility. She has a history of renal impairment. Because the patient has had a diagnosis of CIC "on and off" for several years, she may require ongoing treatment for constipation. Options for this patient are:

A. Avoid prescription constipation therapies and add fiber and prune juice to her diet, since she is already on multiple medications B. Manage with regular use of a stimulant laxative C. Consider a once-daily GC-C agent such as linaclotide or plecanatide D. Consider prucalopride at usual dose E. Unsure

10. In the BURDEN-CIC study, the term used most commonly by patients with CIC (including severe CIC) and healthcare providers to describe their attitude about the condition was:

A. Fine; not a big deal B. Accepting it as part of life C. In control; well managed D. Frustrated E. Unsure

Maintenance is scheduled for 8/7/2023 7:00 AM EST - 8:00 AM EST.

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{{recommendationsB.Title}}

1. Constipation is a problem that affects:

2. As defined by the Rome IV criteria, CIC or "functional constipation" is:

3. The most common mechanism of chronic constipation is:

4. Which of the following agents are defined as stimulant laxatives?

5. A physician in your practice setting says he is prescribing a constipation therapy for a patient and asks you which guanylate cyclase-C agonist is on formulary. The agents in this category are:

6. The 5 HT4 receptor agonists currently approved by the FDA for the treatment of adults with constipation are:

7. A patient in your community pharmacy wants to know if he can take more stool softener (docusate) because his usual dose (100 mg each morning) does not seem to help his "ongoing constipation problem." The most practical approach is:

8. Which of the following statements is true regarding constipation in the hospital setting?

10. In the BURDEN-CIC study, the term used most commonly by patients with CIC (including severe CIC) and healthcare providers to describe their attitude about the condition was:

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Maintenance is scheduled for 8/7/2023 7:00 AM EST - 8:00 AM EST.

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{{recommendationsB.Title}}

1. Constipation is a problem that affects:

2. As defined by the Rome IV criteria, CIC or "functional constipation" is:

3. The most common mechanism of chronic constipation is:

4. Which of the following agents are defined as stimulant laxatives?

5. A physician in your practice setting says he is prescribing a constipation therapy for a patient and asks you which guanylate cyclase-C agonist is on formulary. The agents in this category are:

6. The 5 HT4 receptor agonists currently approved by the FDA for the treatment of adults with constipation are:

7. A patient in your community pharmacy wants to know if he can take more stool softener (docusate) because his usual dose (100 mg each morning) does not seem to help his "ongoing constipation problem." The most practical approach is:

8. Which of the following statements is true regarding constipation in the hospital setting?

10. In the BURDEN-CIC study, the term used most commonly by patients with CIC (including severe CIC) and healthcare providers to describe their attitude about the condition was:

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