1. A diagnosis of breakthrough pain requires _______________.

2. A patient on oxycodone extended-release for chemotherapy-induced neuropathic pain who reports consistent increases in her pain level 1 hour before her scheduled opioid dose in the morning or evening is likely experiencing ________.

3. A patient with cancer pain that is treated with oxycodone extended-release 20 mg twice daily experiences debilitating increases in pain each time she walks her dog. The preferred pharmacologic approach is to _____________.

4. Transmucosal immediate-release fentanyl medications should only be prescribed to patients who are ___________.

5. A patient must be taking at least _________ oxycodone 5 mg tablets each day for more than 1 week to meet the definition of opioid-tolerant from the US Food and Drug Administration.

6. Fentanyl is used in prescription opioid formulations designed to treat cancer-related breakthrough pain because it is ________.

7. The appropriate initial dose of a transmucosal immediate-release fentanyl medication for a patient with cancer-related breakthrough pain is _________.

8. The Risk Evaluation and Mitigation Strategy for transmucosal immediate-release fentanyl medications includes ___________.

9. How often do you NOW PLAN TO stratify your patients with chronic pain for risks of aberrant drug-taking behavior before prescribing long-term opioid therapy?

10. How often do you NOW PLAN TO tailor therapy for breakthrough pain based on the temporal profile and predictability of the episodes?

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