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1. Which of the following statements is correct concerning pharmacodynamics?

A. Pharmacodynamics is concerned with what a drug does to the body B. Pharmacodynamics is concerned with what the body does to a drug C. Pharmacodynamic drug interactions can only be antagonistic D. All of the above are correct

2. The biological effect that results from sporadic sodium intake and lithium is an example of which of the following drug interactions?

A. Pharmacodynamic B. Pharmacokinetic C. Complexation D. None of the above

3. Of the recommended 1000 calorie test meals used in food-effect studies, how many calories are derived from fat?

A. 100-150 B. 200-250 C. 500-600 D. 800-850

4. Grapefruit juice affects the metabolism of numerous oral medications by inhibiting CYP3A4 enzymes in the:

A. Liver B. Gastrointestinal tract C. Kidney D. None of the above

5. Narrow therapeutic index drugs are those where:

A. There is less than a 2-fold difference between the median lethal and median effective dose B. There is less than a 2-fold difference between the minimum toxic and minimum effective concentrations in the blood C. The safe and effective use of the drug requires careful titration and patient monitoring. D. All of the above

6. When kidney function is impaired, it is expected that:

A. Gentamicin elimination will increase B. Gentamicin elimination will decrease C. Gentamicin elimination will not change D. None of the above

7. When a patient is stabilized on a dose of warfarin and a potent inducer of the enzyme CYP2C9 is added to his or her regimen, the dose of warfarin will likely need to be:

A. Increased B. Decreased C. No change in dose will be needed D. None of the above

8. When 2 drugs with similar mechanisms of action produce an effect equal to the sum of the individual effects, the interaction is referred to as:

A. Potentiating B. Anecdotal C. Synergistic D. Additive

9. When a patient takes too much alprazolam and it becomes an emergent situation, the patient is likely to be administered flumazenil to reverse alprazolam's effects. In this sense, flumazenil is considered which of the following?

A. A substrate B. An inhibitor C. An antidote D. An inducer

10. Differences in which of the following are among significant factors that influence patients' responses to medications?

A. Age B. Gender C. Genetics D. All of the above

Evaluation Questions

11. To what extent did the program meet objective #1?

A. Excellent B. Very Good C. Good D. Fair E. Poor

12. To what extent did the program meet objective #2?

A. Excellent B. Very Good C. Good D. Fair E. Poor

13. To what extent did the program meet objective #3?

A. Excellent B. Very Good C. Good D. Fair E. Poor

14. To what extent did the program meet objective #4?

A. Excellent B. Very Good C. Good D. Fair E. Poor

15. Rate the effectiveness of how well the program related to your educational needs:

A. Excellent B. Very Good C. Good D. Fair E. Poor

16. Rate how well the active learning strategies (questions, cases, discussions) were appropriate and effective learning tools:

A. Excellent B. Very Good C. Good D. Fair E. Poor

17. Rate the quality of the faculty:

A. Excellent B. Very Good C. Good D. Fair E. Poor

18. Rate the effectiveness and the overall usefulness of the material presented:

A. Excellent B. Very Good C. Good D. Fair E. Poor

19. Rate the appropriateness of the examination for this activity:

A. Excellent B. Very Good C. Good D. Fair E. Poor

20. Rate the effectiveness of how well the activity related to your practice needs:

A. Excellent B. Very Good C. Good D. Fair E. Poor

21. Rate the effectiveness of how well the activity will help you improve patient care:

A. Excellent B. Very Good C. Good D. Fair E. Poor

22. Will the information presented cause you to change your practice?

A. Yes B. No

23. Are you committed to making these changes?

A. Yes B. No

24. As a result of this activity, did you learn something new?

A. Yes B. No

25. What is your practice setting or area of practice?

A. Community Pharmacy/Independent B. Community Pharmacy/Chain C. Hospital/Health Systems D. Administrative/Pharmacy Director E. Critical Care Pharmacy F. Long-term Care G. Managed Care/PBM H. Oncology/Specialty Pharmacy I. Industry/Manufacturing

26. How many years have you been in practice?

A. <5 B. 5 – 10 C. 11 – 20 D. >20

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