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1. Which immunoglobulin plays the most important role in antibody-mediated immunity?

A. IgA B. IgD C. IgG D. IgM

2. What is the most frequent and symptomatic primary immunodeficiency disorder (PID)?

A. Severe combined immunodeficiency (SCID) B. Common variable immune deficiency (CVID) C. Wiskott-Aldrich syndrome (WAS) D. X-linked agammaglobulinemia (XLA)

3. Patients with severe combined immunodeficiency (SCID) typically present with severe opportunistic infections. Which system do these infections commonly involve?

A. Respiratory tract B. Urinary tract C. Bloodstream D. Joints

4. Hematopoietic stem cell transplantation (HSCT) is the treatment of choice for patients with severe combined immunodeficiency (SCID). However, intravenous (IV)IG is a treatment modality after HSCT in patients that have inadequate function in which cell line?

A. T-cells B. Plasma cells C. Macrophages D. B-cells

5. In an effort to decrease osmolarity of IG preparations, manufacturers may use which of the following as a stabilizer:

A. Glycine B. Glucose C. Sorbitol D. Maltose

6. Which of the following stabilizers should be used with caution when treating patients with renal impairment:

A. Maltose B. Sucrose C. Glucose D. Sorbitol

7. Patients with which untreated PID are more likely to have a severe anaphylactic reaction?

A. Severe combined immunodeficiency (SCID) B. Hyper IgM syndrome (HIGM) C. Wiskott-Aldrich syndrome (WAS) D. Congenital agammaglobulinemia

8. The risk of what type of reaction is more common with subcutaneous IG (SCIG) versus IVIG?

A. Anaphylaxis B. Headache C. Swelling at injection site D. Hemolysis

9. What is a disadvantage of traditional SCIG administration?

A. More systemic adverse effects B. Longer time commitment C. Multiple infusion sites D. Decreased quality of life

10. What is an advantage of IG infusion 10% with recombinant human hyaluronidase?

A. Improved safety profile as compared with SCIG B. Similar peak-to-trough variation as compared with subcutaneous SCIG C. Higher peak levels compared with IVIG D. Less frequent administration compared with IVIG

Maintenance is scheduled for 05/16/2024 5:00 PM EST - 05/17/2024 5:00 AM EST.

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1. Which immunoglobulin plays the most important role in antibody-mediated immunity?

2. What is the most frequent and symptomatic primary immunodeficiency disorder (PID)?

3. Patients with severe combined immunodeficiency (SCID) typically present with severe opportunistic infections. Which system do these infections commonly involve?

4. Hematopoietic stem cell transplantation (HSCT) is the treatment of choice for patients with severe combined immunodeficiency (SCID). However, intravenous (IV)IG is a treatment modality after HSCT in patients that have inadequate function in which cell line?

5. In an effort to decrease osmolarity of IG preparations, manufacturers may use which of the following as a stabilizer:

6. Which of the following stabilizers should be used with caution when treating patients with renal impairment:

7. Patients with which untreated PID are more likely to have a severe anaphylactic reaction?

8. The risk of what type of reaction is more common with subcutaneous IG (SCIG) versus IVIG?

9. What is a disadvantage of traditional SCIG administration?

10. What is an advantage of IG infusion 10% with recombinant human hyaluronidase?

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Maintenance is scheduled for 05/16/2024 5:00 PM EST - 05/17/2024 5:00 AM EST.

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1. Which immunoglobulin plays the most important role in antibody-mediated immunity?

2. What is the most frequent and symptomatic primary immunodeficiency disorder (PID)?

3. Patients with severe combined immunodeficiency (SCID) typically present with severe opportunistic infections. Which system do these infections commonly involve?

4. Hematopoietic stem cell transplantation (HSCT) is the treatment of choice for patients with severe combined immunodeficiency (SCID). However, intravenous (IV)IG is a treatment modality after HSCT in patients that have inadequate function in which cell line?

5. In an effort to decrease osmolarity of IG preparations, manufacturers may use which of the following as a stabilizer:

6. Which of the following stabilizers should be used with caution when treating patients with renal impairment:

7. Patients with which untreated PID are more likely to have a severe anaphylactic reaction?

8. The risk of what type of reaction is more common with subcutaneous IG (SCIG) versus IVIG?

9. What is a disadvantage of traditional SCIG administration?

10. What is an advantage of IG infusion 10% with recombinant human hyaluronidase?

« Return to Activity

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