1. A man, 25 years of age, with a 3-year history of schizophrenia comes to the pharmacy for a refill of his risperidone prescription. He is malodorous, disheveled, and does not make eye contact with the pharmacist during patient counseling. Which symptom domain of schizophrenia is being exhibited by this patient?

2. Several areas of psychosocial functioning can be rated as milestones that indicate achievement or improvement in functioning. Which one of the following is an indicator of better psychosocial functioning for a patient with schizophrenia:

3. In a clinical trial evaluating remission in schizophrenia, what baseline parameter predicted a better chance of remission by the end of the study?

4. Which one of the following statements is TRUE regarding the concepts of remission and recovery in schizophrenia:

5. A patient, 23 years of age, has been taking aripiprazole 20 mg orally once daily for 3 months with improvement in symptoms of schizophrenia. His psychiatrist calls the pharmacy to inquire about an appropriate dose of aripiprazole long-acting injection for this patient. The patient is also taking bupropion XL 300 mg orally once daily for depression. What is the most appropriate recommendation for the pharmacist to make?

6. A prescription is presented to the pharmacist for olanzapine pamoate 300 mg IM every 2 weeks. According to the REMS for olanzapine pamoate, what should the prescription state in order for it to be filled?

7. A patient, 28 years of age, has been maintained on paliperidone palmitate once monthly 234 mg IM every 4 weeks for the past 4 months. A new prescription for paliperidone palmitate every 3 months is presented to the pharmacy for this patient. What is the appropriate dose of paliperidone palmitate every 3 months if the patient has been receiving 234 mg of paliperidone palmitate once monthly?

8. A patient, 30 years of age, is initiating aripiprazole long-acting injection 400 mg IM every 4 weeks. Which of the following oral antipsychotics and time frames is most appropriate for the oral antipsychotic overlap required for aripiprazole long-acting injection?

9. The pharmacist is counseling a patient receiving a LAI antipsychotic injection who has come to the pharmacy to pick up a new prescription for metformin extended-release 500 mg orally at bedtime. The patient tells the pharmacist that they have gained about 30 pounds in the 2 months since starting the LAI injection and has increased blood glucose. Which LAI antipsychotic is the patient most likely receiving?

10. The pharmacist is discussing a new prescription for paliperidone palmitate once monthly with a patient who has been taking oral paliperidone 6 mg once daily for 3 months with a reduction in auditory hallucinations and is improved in disorganized thinking. There is a self-reported decrease in her monthly menstrual cycle. Can this be caused by paliperidone? Which one of the following responses is most appropriate for the pharmacist:

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