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1. Which of the following baseline factors is LEAST likely to influence response to antiviral therapy?

A. Patient age B. HCV genotype C. Presence of cirrhosis D. Resistance mutations

2. SP is a 57-year-old man with newly diagnosed HCV genotype 1a infection. His baseline workup reveals mild hypertension (BP, 142/86 mmHg) and moderately reduced renal function (eGFR 28 mL/min). Which of the following describes the MOST APPROPRIATE treatment option?

A. Ledipasvir/sofosbuvir for 12 weeks B. Elbasvir/grazoprevir for 12 weeks C. Sofosbuvir/simeprevir for 12 weeks D. Pegylated interferon and dose-adjusted ribavirin for 12 weeks

3. Which of the following statements regarding sofosbuvir/velpatasvir is MOST accurate?

A. Sofosbuvir/velpatasvir shows high SVR12 rates (≥95%) across all HCV genotypes B. Sofosbuvir/velpatasvir is superior to sofosbuvir/ribavirin across all HCV genotypes except HCV genotype 3 C. Sofosbuvir/velpatasvir is superior to sofosbuvir/ribavirin in non-cirrhotic patients only D. Sofosbuvir/velpatasvir is superior to sofosbuvir/ribavirin in treatment-naïve patients only

4. Which of the following antiviral regimens is associated with the lowest daily pill burden and shortest potential duration of treatment for appropriate patients?

A. Ledipasvir/sofosbuvir B. Ombitasvir, paritaprevir/ritonavir + dasabuvir C. Elbasvir/grazoprevir D. Daclatasvir/sofosbuvir

Maintenance is scheduled for 8/7/2023 7:00 AM EST - 8:00 AM EST.

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1. Which of the following baseline factors is LEAST likely to influence response to antiviral therapy?

2. SP is a 57-year-old man with newly diagnosed HCV genotype 1a infection. His baseline workup reveals mild hypertension (BP, 142/86 mmHg) and moderately reduced renal function (eGFR 28 mL/min). Which of the following describes the MOST APPROPRIATE treatment option?

3. Which of the following statements regarding sofosbuvir/velpatasvir is MOST accurate?

4. Which of the following antiviral regimens is associated with the lowest daily pill burden and shortest potential duration of treatment for appropriate patients?

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Maintenance is scheduled for 8/7/2023 7:00 AM EST - 8:00 AM EST.

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1. Which of the following baseline factors is LEAST likely to influence response to antiviral therapy?

2. SP is a 57-year-old man with newly diagnosed HCV genotype 1a infection. His baseline workup reveals mild hypertension (BP, 142/86 mmHg) and moderately reduced renal function (eGFR 28 mL/min). Which of the following describes the MOST APPROPRIATE treatment option?

3. Which of the following statements regarding sofosbuvir/velpatasvir is MOST accurate?

4. Which of the following antiviral regimens is associated with the lowest daily pill burden and shortest potential duration of treatment for appropriate patients?

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