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1. Which one of the following statements is TRUE regarding inflammatory bowel disease (IBD)?

A. Inactive disease is a common characteristic of patients with IBD and anemia B. Decreased iron absorption is a risk factor for developing iron deficiency anemia in patients with IBD C. Vitamin B12 deficiency is the most common form of anemia in patients with IBD D. IBD is most common in developing countries in South America and in Australia

2. Which oral iron regimen would deliver the low-dose supplementation of 50 to 120 mg of elemental iron per day?

A. Ferrous fumarate 325 mg; 1 tablet by mouth twice daily B. Ferrous sulfate 325 mg; 2 tablets by mouth twice daily C. Ferrous gluconate 325 mg; 2 tablets by mouth 4 times daily D. Ferrous gluconate 325 mg; 1 tablet by mouth twice daily

3. Which oral iron regimen would you recommend for a patient with iron deficiency anemia when oral therapy is indicated?

A. Ferrous fumarate 325 mg; 1 tablet by mouth once daily B. Ferrous fumarate 150 mg; 2 tablets by mouth twice daily C. Ferrous sulfate 325 mg; 2 tablets by mouth twice daily D. Ferrous gluconate 325 mg; 2 tablets by mouth twice daily

4. Which one of the following beverages is most appropriate to take with oral iron supplements?

A. Orange juice B. Milk C. Tea D. Coffee

5. Which intravenous iron formulation requires the most infusions to complete a total cumulative dose of 1000 mg?

A. Ferric carboxymaltose B. Ferumoxytol C. Iron sucrose D. Ferric gluconate

6. Which intravenous iron formulation requires a test dose prior to the full dose?

A. Ferric carboxymaltose B. Ferumoxytol C. Iron sucrose D. Low molecular weight iron dextran

7. JP is a 28-year-old woman with active Crohn's disease. She is admitted to the hospital and is diagnosed with iron deficiency anemia. JP weighs 60 kg, has a hemoglobin of 9.1 g/dL, a ferritin of 20 µg/L, and a transferrin saturation of 15%. The team has started appropriate induction therapy for the flare-up of disease, but the doctor would like the pharmacist to recommend an iron replacement regimen. What is the most appropriate recommendation?

A. Ferrous fumarate 325 mg once daily B. Ferrous sulfate 325 mg twice daily C. Iron sucrose 200 mg IV; administer 5 doses over a 14-day period D. Ferric carboxymaltose 1000 mg IV daily for 5 days

8. A patient with inflammatory bowel disease is started on oral iron replacement for mild iron deficiency anemia. Which one of the following lab values would indicate an appropriate response?

A. Hemoglobin increase by more than 2 g/dL after 1 week of therapy B. Hemoglobin value of 14 g/dL after 4 weeks of therapy C. Hemoglobin increase by at least 2 g/dL and transferrin saturation greater than 30% after 4 weeks of therapy D. Hemoglobin increase by at least 1 g/dL and transferrin saturation of 25% after 6 weeks of therapy

9. Which of the following would be an appropriate use of erythropoietin for the treatment of patients with iron deficiency anemia (IDA)?

A. Add erythropoietin to oral iron supplementation to enhance the response B. Use erythropoietin in combination with intravenous (IV) iron as initial therapy upon the first diagnosis of IDA C. Use erythropoietin as monotherapy for the treatment of IDA D. Add erythropoietin to IV iron after nonresponse to IV iron monotherapy